PURPURA FULMINANS AS AN ATYPICAL PRESENTATION OF A FREQUENT PATHOLOGY. REPORT OF TWO CASES

Abstract

Purpura fulminans (PF) is an acute disease commonly associated with meningococcemia or invasive streptococcal disease, and typically characterized by purpuric skin lesions. It is not usually a typical presentation of invasive Staphylococcus aureus infections, although its appearance is usually a sign of poor prognosis that, even with all therapeutic and diagnostic efforts, leads to death. Its belonging to the normal human microbiota in skin and mucous membranes, associated with its ability to colonize different biomedical devices, makes Staphylococcus aureus a frequent cause of both extra-hospital and intra-hospital infections; It has a number of virulence factors such as superantigenic, exfoliative toxins and others that damage the cell membrane that generate a diverse range of presentations that can range from skin and soft tissue infections without systemic repercussions, to PF with rapid deterioration and subsequent death. . Two cases of patients with staphylococcemia that debuted through purpura are described.